The Anticonvulsants
Seizure Classification
Complex Partial Seizure
Partial Become Generalized
Generalized Seizures
No confused state after seizure
Myoclonic Seizures
Clonic Seizures
Tonic Seizures
Tonic-Clonic Seizures (Grand Mal)
Atonic Seizures
Anticonvulsants…A Plethora Of Drugs
The Hydantoins
Phenytoin (Dilantin) - Prototypic Drug
Dilantin - Mechanism of Action
Hydantoins -Adverse Side Effects
The Barbiturates
Mechanism Of Action
Reduces neurotransmitter release thereby quieting the brain
Adverse Side Effects
The Iminostilbenes
Mechanism of Action
Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)
Succinimides
Aplastic Anemia
Renal and hepatic toxicity
Stevens-Johnson Disease
Necrotic vasculitis may be present (capillary damage)
Cause ????
Benzodiazepines
Valproic Acids
Anticonvulsants - Medical Uses
Tegretol
Clinical Considerations
Are there any external triggers which could set off the seizure ??? (light, sound, fatigue, odors)
Are the patients under unusual stress - divorce, family deaths, etc.
Have a good seizure plan in the clinic
Email: David.Arnall@NAU.EDU , DAArnall@AOL.COM
Home Page: http://jan.ucc.nau.edu/~daa/pt675/
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