Create a Baby Lab

Baby Lab

Artwork by Maria Rascon

Purpose: To demonstrate the principles of Mendelian genetics and sex determination, including the concepts of allele, phenotype, genotype, dominant, recessive, codominant, homozygous and heterozygous by creating a simulated baby.

Materials: Two pennies, art supplies, paper.

Procedure:

1) Working with a partner, determine the genotype of the baby by flipping pennies. "Mom" flips one penny to choose an allele for her egg and "Dad" flips the other to choose an allele for his sperm. (Note that the gender of the baby is a special case and is determined by dad alone. Boys are XY and girls are XX. Mom can give only an X but dad can give either an X or a Y.)

2) Record the alleles which resulted from the coin flips, and put "sperm and egg" together. (You cannot pick the traits you want; life doesn't work that way!) Write down baby's genotype for each trait in Table 1. Heads represents allele #1 and tails represents allele #2.

3) Record the baby's phenotype in Table 1 by looking up the genotype you got in the Genotype/Phenotype Reference Sheet. Note: Dominant alleles are written with an uppercase letter and recessive alleles are written as lowercase letters. Dominant alleles mask the expression of recessive ones. Co-dominant alleles are written as uppercase letters with a subscript. Co-dominant alleles result in a phenotype that is blended.

4) Repeat steps 1, 2, and 3 for all traits and then draw, color, and name your creation. Remember that you are drawing a baby's face that represents the traits you got - not a child's or an adult's (no tattoos, no mustaches, no piercings, etc., and not too much hair!)


Concluding Questions:

1. Why is the coin flip used to represent the selection of alleles?

2. Define the following terms:

allele-

phenotype-

genotype-

dominant-

recessive-

codominant-

homozygous-

heterozygous-

chromosome-

locus-

gene-


Results:

Table 1: Check here indicating whether you are the mom or the dad and fill in the data below.

Mom's Name: ________________

Dad's Name _________________

Baby's Name: ________________

Trait
Heads Tails
Allele from Mom
Allele from Dad
Genotype
Phenotype

Gender

X Y
______X______
_____________
_____________
_____________

Face Shape

R r
_____________
_____________
_____________
_____________

Chin Shape

N n
_____________
_____________
_____________
_____________

Chin Dimple

A a
_____________
_____________
_____________
_____________

Freckles

F f
_____________
_____________
_____________
_____________

Cheek Dimples

D d
_____________
_____________
_____________
_____________

Lip Thickness

T t
_____________
_____________
_____________
_____________

Eye Brows

B b
_____________
_____________
_____________
_____________

Eye Shape

W w
_____________
_____________
_____________
_____________

Eyelashes

L l
_____________
_____________
_____________
_____________

Ear Shape

R r
_____________
_____________
_____________
_____________

Ear Lobes

F f
_____________
_____________
_____________
_____________

Widow's Peak

W w
_____________
_____________
_____________
_____________

Hair Curliness

C1 C2
_____________
_____________
_____________
_____________

Eyebrow Color

D1 D2
_____________
_____________
_____________
_____________

Eye Width

W1 W2
_____________
_____________
_____________
_____________

Eye Size

S1 S2
_____________
_____________
_____________
_____________

Mouth Size

M1 M2
_____________
_____________
_____________
_____________

Nose Size

P1 P2
_____________
_____________
_____________
_____________

Birth Mark

B1 B2
_____________
_____________
_____________
_____________

Skin Tone

S1 S2
_____________
_____________
_____________
_____________
Polygenic Trait
(4 coin flips)
Alleles from Mom
Alleles from Dad
Genotype
Phenotype

Hair Color

A, B a, b
#1____ #2____
#1____ #2____
__ __ /__ __
_____________

Eye Color

A, B a, b
#1____ #2____
#1____ #2____
__ __ /__ __
_____________


Genotype/Phenotype Reference Sheet

Trait
Genotype/Phenotype (Homozygous for Allele 1)
Genotype/Phenotype (Heterozygous)
Genotype/Phenotype (Homozygous for Allele #2)

Face Shape

RR

Round

round face
Rr

Round

round face
rr

Square

square face

Chin Shape

NN

Noticeable

noticeable chin
Nn

Noticeable

noticeable chin
nn

Less Noticeable

less noticeable chin

Chin Dimple

AA

Absent

chin dimple absent
Aa

Absent

chin dimple absent
aa

Present

chin dimple present

Freckles

FF

Present

freckles
Ff

Present

freckles
ff

Absent

no freckles

Cheek Dimples

DD

Present

dimples
Dd

Present

dimples
dd

Absent

no dimples

Lip Thickness

TT

Thick

thick lips
Tt

Thick

thick lips
tt

Thin

thin lips

Eye Brows

BB

Bushy

bushy eyebrows
Bb

Bushy

bushy eyebrows
bb

Fine

fine eyebrows

Eye Shape

WW

Wide

wide eyes
Ww

Wide

wide eyes
ww

Round

round eyes

Eyelashes

LL

Long

long lashes
Ll

Long

long lashes
ll

Short

short lashes

Ear Shape

RR

Long

long ears
Rr

Long

long ears
rr

Round

round ears

Ear Lobes

FF

Free

earlobes free
Ff

Free

earlobes free
ff

Attached

earlobes attached

Widow's Peak

WW

Present

widow's peak
Ww

Present

widow's peak
ww

Absent

no widow's peak

Hair Curliness

C1C1

Curly

curly hair
C1C2

Wavy

wavy hair
C2C2

Straight

straight hair

Eyebrow Color

D1D1

Darker than hair

darker eyebrows
D1D2

Same as hair

eyebrows same as hair
D2D2

Lighter than hair

lighter eyebrows

Eye Width

W1W1

Close Together

eyes close together
W1W2

Average

eyes average
W2W2

Far apart

eyes far apart

Eye Size

S1S1

Large

eyes large
S1S2

Medium

eyes medium
S2S2

Small

eyes small

Mouth Size

M1M1

Wide

mouth wide
M1M2

Medium

mouth average
M2M2

Narrow

mouth narrow

Nose Size

P1P1

Small

small nose
P1P2

Medium

medium nose
P2P2

Large

large nose

Birth Mark (mole)

B1B1

Left cheek

left
B1B2

Absent

absent
B2B2

Right cheek

right

Skin Tone

S1S1

Light

light skin
S1S2

Medium

medium skin
S2S2

Dark

dark skin

Hair Color

AABB=Black

AaBB=Dark Brown

aaBB=Blond

AABb=Black

AaBb=Light Brown

aaBb=Blond

AAbb=Red

Aabb=Dark Blond

aabb=white (albino)

Eye Color

AABB=Deep Brown

AaBB=Greenish Brown

aaBB=Green

AABb=Deep Brown

AaBb=Light Brown

aaBb=Light Blue

AAbb=Brown

Aabb=Gray-Blue

aabb=Pink