Etiology

Inherited disorder

Autosomal dominant

Predilection

Young children

Individualsof Mediterranean decent

Location

Systemic disease

Thalasemia Major=severe symptoms

Thalasemia Minor=asymptomatic or mild symptoms

Clinical Appearance

Yellowish skin pallor, fever maliaise, weakness, enlarged liver and spleen

Prominent cheekbones, drepression of bridge of nose prominent premaxilla protrusion or flarin of maxillary anterior teeth

Microscopic Features

Atypical trabecular patter "salt and pepper" pattern

Thinning of the lamina dura

Circular radiolucencies in the alveolar bone

Treatment

Experimental

Diagnostic Process

Clinical

Laboratory

Photos Gallery

Photo 1
Photo 2