Etiology

Inherited disorder

Autosomal dominant

Abnormal hemoglobin

Predilection

Prior to 30 year of age

Blacks

Individuals of Mediterranean origin

Greater in females

Location

Systemic disease

Clinical Appearance

Weakness

Fatigue

Shortness of breath

Joint pain

Nausea

Radiographic Features

Loss of trabeculation with large irregular marrow spaces

Microscopic Features

Sickle-shaped red blood cells

Treatment

Palliative

Oxygen

IV fluid

Diagnostic Process

Laboratory

Photos Gallery

Photo 1